Colloidal Silver (CS) as an Antiseptic: Two opposing viewpoints

Colloidal Silver (CS) as an Antiseptic: Two opposing viewpoints

CS preparations for topical and/or oral use were subsequently developed to overcome the astringency of, and staining by, simple silver salts[2] while retaining the long-known antiseptic properties of metallic silver.[3] The older preparations, pre-1910, usually contained high levels of oxidized silver (Ag+), not precipitated by isotonic salt solutions, made from silver nitrate and various carri...

Iodine as an Antiseptic

Polyhexanide - safety and efficacy as an antiseptic.

BACKGROUND Polyhexamethylene biguanide hydrochloride/polyhexanide/polyaminopropyl biguanide (PHMB) is used as a disinfectant and antiseptic. This article discusses the use of the substance as an antiseptic. We summarise published data on its antimicrobial effect in vitro and its clinical effect and safety when used on skin, wounds and mucosa.MATERIAL AND METHOD A literature search was conducted...

Silver coated aluminium microrods as highly colloidal stable SERS platforms.

We report on the fabrication of a novel material with the ability to remain in solution even under the very demanding conditions required for structural and dynamic characterization of biomacromolecule assays. This stability is provided by the increase in surface area of a low density material (aluminium) natively coated with a very hydrophilic surface composed of aluminium oxide (Al(2)O(3)) an...

An evaluation of acute toxicity of colloidal silver nanoparticles.

Tests for acute oral toxicity, eye irritation, corrosion and dermal toxicity of colloidal silver nanoparticles (AgNPs) were conducted in laboratory animals following OECD guidelines. Oral administration of AgNPs at a limited dose of 5,000 mg/kg produced neither mortality nor acute toxic signs throughout the observation period. Percentage of body weight gain of the mice showed no significant dif...